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TWINRIX is the only dual hepatitis A and B vaccine.

TWINRIX is a vaccine used in adults, adolescents, children, and infants to prevent hepatitis A and B diseases.

The TWINRIX vaccine works by helping your body produce its own protection (antibodies) against hepatitis A and B.

TWINRIX is administered as an intramuscular injection by a healthcare professional.

Possible side effects

Adults
Side effects that occurred in adults during clinical trials with the standard (3 dose) and the rapid (4 dose) TWINRIX vaccination schedule were:

Very common (more than 10% of doses): Pain or discomfort, redness at the injection site, headache and tiredness

Common (between 1% and 10% of doses): Swelling at the injection site, diarrhea, nausea, vomiting and generally feeling unwell

Uncommon (between 0.1% and 1% of doses): Fever (over 37.5°C), dizziness, upper respiratory tract infection, and aching muscles

Rare (between 0.01% and 0.1% of doses): Swollen glands in the neck, armpit or groin, loss of appetite, pins and needles, low blood pressure, rash and itching, muscle and joint pain and flu- like symptoms, such as high temperature, sore throat, runny nose, cough and chills

Very rare (less than 0.01% of doses): Hives

Children
Side effects that occurred in children who received the standard (3 dose) TWINRIX Junior vaccination schedule were:

Very common (more than 10% of doses): Pain and redness at the injection site

Common (between 1% and 10% of doses): Swelling at the injection site, fever (more than 37.5°C), irritability, drowsiness, headache, loss of appetite, diarrhea, nausea, vomiting and generally feeling unwell

Uncommon (between 0.1% and 1% of doses): Rash

Rare (between 0.01% and 0.1% of doses): Swollen glands in the neck, armpit or groin, dizziness and hives

Very rare (less than 0.01% of doses): Pins and needles, loss of skin sensitivity to pain or touch, numbness of the arms and legs, low blood pressure, rash and itching, aching muscles and joint pain and flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills

Side effects that occurred in children during clinical trials who received the alternate (2 dose) TWINRIX vaccination schedule were:

Very common (more than 10% of doses): Pain and redness at the injection site, tiredness, headache, irritability and loss of appetite

Common (between 1% and 10% of doses): Swelling at the injection site, fever, drowsiness, stomach and digestive complaints

Do not be alarmed by this list of possible side effects. It is likely that you will have no side effects from vaccination. This is not a complete list of side effects. For any unexpected effects while taking TWINRIX, contact your healthcare provider.

Anyone experiencing a fever or anything more serious than a minor cold should postpone vaccination. Pregnant women should discuss the possible risks and benefits of vaccination with their healthcare provider.